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Module 3 / Lesson 9.4.3

New Tools for Pandemics as Strategic Weapons

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This chapter evaluates how converging biotechnologies, AI, and rapid vaccine platforms create both defensive and offensive potential, transforming pandemics into possible strategic weapons, and assess the associated ethical, policy, and security implications.

Learning: Read the following to get to know more about the dual-use risk of biotechnology.

Reflection: As you read it, how does the introduction of AI into pathogen design fundamentally change the nature of the bioweapon threat compared to historical biological warfare? (Hint: Think about expertise and deterrence).

1. Concept Overview

Modern biotechnology allows scientists to design and edit pathogens and to rapidly build custom countermeasures. When these two capacities combine, they introduce an asymmetric risk: an actor could theoretically vaccinate its own population, then release an engineered pathogen to harm others.

At an even more speculative frontier, tools like CRISPR - Cas9 could theoretically enable genetically selective bioweapons, designed to target people carrying certain genetic markers disproportionately found in specific ethnic groups.

This convergence redefines biosecurity: the same scientific breakthroughs that safeguard humanity could, under malign intent or accident, endanger it.

Optional Reading: This concise piece outlines how advances in both artificial intelligence and biotechnology are creating novel biosecurity risks, especially through dual-use mechanisms. It provides clear policy suggestions to manage those risks: Mitigating Risks from Dual-Use Research

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x-Risk Course · Existential Risk: An Open Course

Designed and led by Professor Stephen H. Shore. Online contributors: Abbad Ali and Suyog Thengale.

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Original course materials © Stephen H. Shore · CC BY-NC 4.0. Third-party materials retain their own terms.

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